Human Reproduction, Vol. 18, No. 9, 1858-1863,
September 2003
© 2003 European Society of Human Reproduction and Embryology
Elective single embryo transfer yields good delivery rates in oocyte donation
1 The Family Federation of Finland, Infertility Clinic, PO Box 849, FIN-00101 Helsinki and 2 Department of Obstetrics and Gynaecology, University Central Hospital of Helsinki, FIN-00290 Helsinki, Finland
3 To whom correspondence should be addressed. e-mail: viveca.soderstrom-anttila{at}vaestoliitto.fi
BACKGROUND: High pregnancy rates have been noted after oocyte donation (OD). Multiple pregnancies should be avoided, because oocyte recipients have an increased risk of obstetric complications. METHODS: We analysed our OD results from 2000–2001 when elective single embryo transfer (eSET) was introduced as a recommended policy for all recipients if at least one good quality embryo was available. The results were compared with those achieved in 1998–1999, when usually two embryos were transferred (double embryo transfer, DET). Between 1998 and 2001, 100 healthy women donated oocytes and 135 fresh embryo transfers were carried out. The mean age of the donors was 31 years and that of the recipient women was 35 years. RESULTS: The proportion of eSET of all OD transfers was 17.1% in 1998–1999 and 61.0% in 2000–2001. There was no statistically significant difference in clinical pregnancy (36.8 versus 45.8%) and delivery rates (31.6 versus 33.9%) per embryo transfer between the two time periods. The proportion of twins declined from 29% (1998–1999) to 10% (2000–2001). The delivery rate was similar after eSET and DET (32.6 versus 32.1% respectively). CONCLUSIONS: By increasing the proportion of eSETs it is possible to reduce the number of twins without affecting delivery rates in oocyte recipients.
Key words: multiples/oocyte donation/pregnancy rate/recipients/single embryo
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  Z. Veleva, S. Vilska, C. Hyden-Granskog, A. Tiitinen, J. S. Tapanainen, and H. Martikainen Elective single embryo transfer in women aged 36-39 years Hum. Reprod., August 1, 2006; 21(8): 2098 - 2102. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Bodri, V. Vernaeve, F. Figueras, R. Vidal, J.J. Guillen, and O. Coll Oocyte donation in patients with Turner's syndrome: a successful technique but with an accompanying high risk of hypertensive disorders during pregnancy Hum. Reprod., March 1, 2006; 21(3): 829 - 832. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. M.R. Gerris Single embryo transfer and IVF/ICSI outcome: a balanced appraisal Hum. Reprod. Update, March 1, 2005; 11(2): 105 - 121. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Thurin, J. Hausken, T. Hillensjo, B. Jablonowska, A. Pinborg, A. Strandell, and C. Bergh Elective Single-Embryo Transfer versus Double-Embryo Transfer in in Vitro Fertilization N. Engl. J. Med., December 2, 2004; 351(23): 2392 - 2402. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Mirkin, G. Nikas, J.-G. Hsiu, J. Diaz, and S. Oehninger Gene Expression Profiles and Structural/Functional Features of the Peri-Implantation Endometrium in Natural and Gonadotropin-Stimulated Cycles J. Clin. Endocrinol. Metab., November 1, 2004; 89(11): 5742 - 5752. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. Buckett and S. L. Tan What is the most relevant standard of success in assisted reproduction?: The importance of informed choice Hum. Reprod., May 1, 2004; 19(5): 1043 - 1045. [Abstract] [Full Text] [PDF]
|
|